論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	その他(不明)
表題	Risk factors in patients treated with surgical drainage for rhinogenic intracranial complications: a nationwide study.
掲載誌名	正式名：Rhinology 略　 称：Rhinology ISSNコード：03000729/03000729
掲載区分	国外
巻・号・頁	63(4),pp.397-404
著者・共著者	M Morita, K Tarasawa, H Hidaka, Y Yun, K Fujimori, K Fushimi, S Hamada, M Asako, R Kawachi, M Yagi, H Iwai
発行年月	2025/08
概要	BACKGROUND:Data on risk factors for rhinogenic intracranial complications (RICs) including cerebral abscess have been limited. Using a nationwide database, the aim was to identify the factors related to mortality and delayed discharge.METHODOLOGY:Data of 326 patients between 2012 and 2022 were extracted from a Japanese inpatient database. The main outcome was survival at discharge. In a subgroup analysis of the 316 surviving patients, the outcome was delayed discharge.RESULTS:The mortality rate was 3.1%. Logistic regression analyses identified intracerebral complications more than one surgical intervention and consciousness level evaluated by the Japan Coma Scale (JCS): JCS I and JCS≥ II as risk factors for mortality. Concurrent interventions of intracranial and sinonasal drainage was identified as a factor associated with decreased risk.CONCLUSIONS:Although RICs are rare, with decreasing mortality due to progress in imaging and clinical strategies, they remain the most severe complications of rhinosinusitis. Subdural and/or intracerebral abscess, consciousness level at admission, and more than one surgical intervention were found to be risk factors for mortality. Conversely, concurrent interventions, intracranial and sinonasal drainage, contributed to reducing this risk.
DOI	10.4193/Rhin25.057
PMID	40445119