| 論文種別 | 原著(症例報告除く) |
| 言語種別 | 英語 |
| 査読の有無 | その他(不明) |
| 表題 | Extended Follow-Up of Robot-Assisted Partial Nephrectomy for Renal Hilar Tumor: A Prospective Multi-Institutional Study (ROBOHIT Trial). |
| 掲載誌名 | 正式名：International journal of urology : official journal of the Japanese Urological Association 略 称：Int J Urol ISSNコード：14422042/09198172 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.Online ahead of print |
| 著者・共著者 | Jun Teishima, Ryoichi Shiroki, Toshio Takagi, Masatoshi Eto, Shuichi Morizane, Toshinari Yamasaki, Yasuo Kohjimoto, Fumiya Hongo, Takuya Tsujino, Kensuke Bekku, Nobuyuki Hinata, Atsushi Okada, Tetsuya Yoshida, Tsunenori Kondo, Naoki Kawamorita, Hayato Yamamoto, Shuji Isotani, Masaki Shimbo, Jun Nagayama, Kunihisa Yamaguchi, Hidefumi Kinoshita, Hideaki Miyake |
| 発行年月 | 2025/05 |
| 概要 | OBJECTIVES:We aimed to evaluate the long-term oncological and functional outcomes after robot-assisted partial nephrectomy (RAPN) for renal hilar tumors.METHODS:A total of 22 academic hospitals in Japan participated in a prospective, multicenter, single-arm, open-label trial with a 2-year enrollment period. After undergoing RAPN, 105 patients with clinical T1 renal hilar tumors were followed up for 5 years and evaluated. Recurrence-free survival, overall survival, and trends of renal function were set as oncological and functional outcomes.RESULTS:Five-year overall survival and recurrence-free survival were 98.0% and 89.2%, respectively. Mean estimated glomerular filtration rates (eGFRs) were 69.031 mL/min preoperatively, and were 59.374, 58.334, 58.221, 56.975, and 59.602 mL/min at 1, 2, 3, 4, and 5 years after surgery, respectively. While eGFR was significantly lower than the preoperative one at all points (p < 0.001), eGFRs at 1 and 5 years after surgery did not differ significantly (p = 0.793).CONCLUSION:After long-term follow-up, RAPN for clinical T1 renal hilar tumors continues to provide functional and oncological outcomes equivalent to those in the perioperative period.TRIAL REGISTRATION:The study protocol was registered in the Japan Registry of Clinical Trials (jRCT1052190005, UMIN000023968). |
| DOI | 10.1111/iju.70116 |
| PMID | 40387294 |