論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	その他(不明)
表題	A multicenter trial evaluating the short-term outcomes of intracorporeal versus extracorporeal anastomosis in laparoscopic colectomy for overweight and obese patients with colon cancer: a secondary analysis of the ICAN study.
掲載誌名	正式名：Surgery today 略　 称：Surg Today ISSNコード：14362813/09411291
掲載区分	国外
巻・号・頁	pp.Online ahead of print
著者・共著者	Emi Ota, Jun Watanabe, Hirokazu Suwa, Keitaro Tanaka, Tomohiro Yamaguchi, Hiroki Hamamoto, Atsushi Nishimura, Fumihiko Fujita, Heita Ozawa, Kenji Kobayashi, Tomoaki Okada, Yukitoshi Todate, Takeshi Naitoh
発行年月	2025/08
概要	PURPOSE:The safety and benefits of intracorporeal anastomosis (ICAN) in overweight and obese colon cancer patients remain unclear. This study aimed to evaluate the short-term outcomes of ICAN compared to extracorporeal anastomosis (ECAN) in this population.METHODS:This nationwide multicenter retrospective cohort study included 46 institutions. Body mass index (BMI) ≥ 25 kg/m2 in patients with clinical stage 0-III colon adenocarcinoma who underwent laparoscopic colectomy were assessed using propensity score matching to compare ICAN and ECAN.RESULTS:Between January 2020 and December 2021, 361 patients were analyzed (ICAN, n = 191; ECAN, n = 170). ICAN was associated with a longer operative time (252 vs. 232 min, p < 0.001), but significantly less blood loss (5 vs. 15.5 ml, p < 0.001) and a shorter wound length (4 vs. 5 cm, p < 0.001). There were no significant differences in the intraoperative (1.6 vs. 1.8%) or postoperative complication rates (9.4 vs. 7.6%). The time to first stool passage was shorter in the ICAN group (3 (IQR 2-4) vs. 3 (IQR 3-5) days, p < 0.001).CONCLUSIONS:ICAN is safe and beneficial for overweight and obese patients undergoing laparoscopic colectomy, offering reduced blood loss, smaller incisions, and a faster bowel recovery.TRIAL REGISTRATION:This study was registered in the UMIN Clinical Trials Registry System in 2022 (UMIN000047994).
DOI	10.1007/s00595-025-03117-8
PMID	40841446