論文種別 総説
言語種別 英語
査読の有無 査読あり
表題 rTMS Therapy for Eating Disorders: Scoping Review on Efficacy, Safety, Stimulation Parameters and Study Subjects
掲載誌名 正式名:European eating disorders review : the journal of the Eating Disorders Association
略  称:Eur Eat Disord Rev
ISSNコード:10990968/10724133
掲載区分国外
巻・号・頁 pp.Online ahead of print
著者・共著者 Shun Takahashi, Shunichiro Ikeda, Masaya Ueda, Tomoko Harada, Ryouhei Ishii
発行年月 2025/10
概要 OBJECTIVE:Repetitive transcranial magnetic stimulation (rTMS) has potential as a therapeutic tool for eating disorders. In this scoping review, we examine the efficacy and safety of rTMS therapy for eating disorders besides stimulation parameters and the clinical statuses of participants.METHOD:Following PRISMA-ScR framework, we searched four databases (PubMed, Scopus, Web of Science and PsycInfo) to review clinical interventional studies using rTMS for patients with eating disorders.RESULTS:Thirty-two studies were included. Benefits of rTMS on mood or eating disorder symptoms were reported for patients with anorexia nervosa. Meanwhile, there was improvement in binge eating and impulsivity in patients with bulimia nervosa, but without statistical significance in randomised controlled studies. There were no serious adverse events in relation to rTMS therapy. Stimulation of the left dorsolateral prefrontal cortex at high frequency with 20,000 stimulations was shown to be widely adopted in research on rTMS therapy for eating disorders.CONCLUSION:The number of pulses to the left dorsolateral prefrontal cortex may have been insufficient. The dorsomedial prefrontal cortex is suggested to be an effective stimulation site for patients with binge-purge symptoms. Future research should focus on optimising stimulation parameters including the frequency, the intensity, the session number, and the stimulation site.
DOI 10.1002/erv.70046
PMID 41163241