| 論文種別 | 原著(症例報告除く) |
| 言語種別 | 英語 |
| 査読の有無 | その他(不明) |
| 表題 | Adverse Events of EUS-Guided Biliary Drainage for Malignant Biliary Obstruction: A Large Multicenter Study. |
| 掲載誌名 | 正式名：Journal of hepato-biliary-pancreatic sciences 略 称：J Hepatobiliary Pancreat Sci ISSNコード：18686982/18686974 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.Online ahead of print |
| 著者・共著者 | Masahiro Itonaga, Takeshi Ogura, Mamoru Takenaka, Kazuyuki Matsumoto, Hideyuki Shiomi, Shuhei Shintani, Hideki Kamada, Taro Yamashita, Koichiro Mandai, Masanori Asada, Hajime Imai, Kotaro Takeshita, Tsukasa Ikeura, Nao Fujimori, Makiko Kinoshita, Kenji Ikezawa, Satoshi Sugimori, Koh Kitagawa, Ryota Sagami, Masahito Kokubu, Taira Kuroda, Nobu Nishioka, Keiichi Hatamaru, Kosuke Minaga, Ke Wan, Toshio Shimokawa, Masayuki Kitano |
| 発行年月 | 2025/12 |
| 概要 | BACKGROUND AND AIMS:This study aimed to evaluate adverse events (AEs) for endoscopic ultrasound-guided biliary drainage (EUS-BD) and identify risk factors for early AEs and recurrent biliary obstruction (RBO).METHODS:A multicenter retrospective study was conducted using a common database of 21 Japanese referral centers.RESULTS:A total of 616 patients who underwent EUS-BD, including endoscopic ultrasound-guided choledochoduodenostomy (n = 107), hepaticogastrostomy (n = 487), and hepaticojejunostomy (n = 22), for malignant biliary obstruction were analyzed. Early AEs occurred in 13.6% of patients. Independent risk factors for all AEs included procedure time ≥ 32 min (odds ratio [OR] 1.82) and antiplatelet/anticoagulant use (OR 2.15). A risk factor for peritonitis included electrocautery use (OR 3.87), while bleeding risk was increased with antiplatelet/anticoagulant use (OR 7.19) and performance status > 2 (OR 5.26). The use of plastic stents was associated with a higher risk of a shorter time to RBO. AE and RBO rates did not significantly differ among the three EUS-BD approaches.CONCLUSIONS:Patients on antiplatelet and/or anticoagulation therapy should be aware of the increased risk of AEs of EUS-BD. In addition, it is important to minimize procedure time, avoid the use of electrocautery, and use a metal stent to prevent early AEs and RBO. |
| DOI | 10.1002/jhbp.70055 |
| PMID | 41454434 |