| 論文種別 | 原著(症例報告除く) |
| 言語種別 | 英語 |
| 査読の有無 | その他(不明) |
| 表題 | Prognostic scoring systems reflect the prognosis of patients with metastatic spinal tumors who underwent spinal surgery in recent cases: JASA multicenter prospective study. |
| 掲載誌名 | 正式名：Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 略 称：J Orthop Sci ISSNコード：14362023/09492658 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.Online ahead of print |
| 著者・共著者 | Masahiro Iinuma, Takeo Furuya, Yuki Shiratani, Akinobu Suzuki, Hidetomi Terai, Takaki Shimizu, Kenichiro Kakutani, Yutaro Kanda, Hiroyuki Tominaga, Ichiro Kawamura, Masayuki Ishihara, Masaaki Paku, Yohei Takahashi, Toru Funayama, Kosei Miura, Eiki Shirasawa, Hirokazu Inoue, Atsushi Kimura, Takuya Iimura, Hiroshi Moridaira, Hideaki Nakajima, Shuji Watanabe, Koji Akeda, Norihiko Takagami, Kazuo Nakanishi, Hirokatsu Sawada, Koji Matsumoto, Masahiro Funaba, Hidenori Suzuki, Haruki Funao, Tsutomu Oshigiri, Takashi Hirai, Bungo Otsuki, Kazu Kobayakawa, Koji Uotani, Hiroaki Manabe, Shinji Tanishima, Ko Hashimoto, Chizuo Iwai, Daisuke Yamabe, Akihiko Hiyama, Shoji Seki, Yuta Goto, Masashi Miyazaki, Kazuyuki Watanabe, Toshio Nakamae, Takashi Kaito, Hiroaki Nakashima, Narihito Nagoshi, Satoshi Kato, Shiro Imagama, Kota Watanabe, Gen Inoue, Seiji Ohtori, Hisateru Niki |
| 発行年月 | 2026/01 |
| 概要 | BACKGROUND:The incidence of cancer and related deaths has increased substantially, with bone commonly serving as a metastatic site. Metastatic spinal tumors severely impair quality of life and activities of daily living. Prognostic scoring systems such as the revised Tokuhashi and Tomita scores are widely used in surgical decision-making for these tumors. However, their accuracy for recent cancer cases is unclear due to advances in cancer therapy.METHODS:This multicenter, prospective study by the Japan Association of Spine Surgeons with Ambition analyzed 413 surgical cases for metastatic spinal tumors from October 2018 to March 2021. Of these, 272 cases with complete data were included. The Kaplan-Meier method, log-rank test, and statistical analysis were used to assess the association between survival and prognostic scores.RESULTS:Both the revised Tokuhashi and Tomita scores significantly stratified patients by survival (P < 0.01). The revised Tokuhashi score accurately predicted survival in 60.3 % of patients, underestimated it in 33.1 %, and overestimated it in 6.6 %. Significant score differences were found among groups with different survival durations. However, differentiating between <6-month and 6-12-month survival periods was difficult.CONCLUSIONS:The revised Tokuhashi and Tomita scores remain valid tools for predicting prognosis in patients undergoing surgery for metastatic spinal tumors. Nonetheless, these systems tend to underestimate survival in recent cases, particularly in short-term prognoses. Updating the scoring criteria may be necessary to reflect advancements in cancer therapy and extended patient survival. |
| DOI | 10.1016/j.jos.2026.01.003 |
| PMID | 41571569 |