論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	その他(不明)
表題	Dispatcher-assisted cardiopulmonary resuscitation for out-of-hospital cardiac arrest patients: a site-level analysis of the PAROS trial.
掲載誌名	正式名：Resuscitation plus 略　 称：Resusc Plus ISSNコード：26665204/26665204
掲載区分	国外
巻・号・頁	27,pp.101193
著者・共著者	Fahad Javaid Siddiqui, Stephanie Fook-Chong, Nur Shahidah, David Pflug, Benjamin Sieu-Hon Leong, Sang Do Shin, Hyun Wook Ryoo, Hyun Ho Ryu, Chih-Hao Lin, Chan-Wei Kuo, Marcus Eng Hock Ong, PAROS Clinical Research Network:Kajino K et al.
発行年月	2025/12
概要	OBJECTIVES:The study aimed to examine the influence of contextual settings on the complex OHCA intervention outcomes thereby providing evidence to guide managers and policymakers in optimizing implementation strategies. Our secondary analysis of an international multi-site trial examined site-level effectiveness of comprehensive versus basic Dispatcher-Assisted CPR (DACPR) interventions on bystander CPR rates, hypothesizing site-specific variation and declining variability as an early sign.METHODS:Using 2009-2018 data from the Pan-Asian Resuscitation Outcomes Study (PAROS), we compared monthly and quarterly trends in BCPR rates at selected PAROS sites before and after the intervention. Interrupted time series analysis was performed using regression of monthly BCPR rates for the pre- and post-intervention periods.RESULTS:Six PAROS sites contributed 37,872 out-of-hospital cardiac arrest (OHCA) cases from January 2009 to June 2018. Comprehensive package sites showed consistent improvement in average monthly BCPR rates, with absolute increases ranging from 4.2 to 30.8 percentage points. Sharper post-intervention increases in DACPR rates were observed, indicated by positive site-wise regression coefficient differences (0.07-0.38). However, some sites experienced an initial post-intervention slowdown of the pre-existing trend. The two Basic package sites also improved their BCPR rates by 9.3 and 25.1 percentage points, though the shorter pre-intervention periods limited meaningful interpretation of the rate of change (0.22 & -0.33).CONCLUSION:Both intervention packages improved BCPR rates, with most sites showing steeper improvements post-intervention. However, variations in timing and magnitude between sites highlight differing levels of system readiness and implementation rigor. Reduced variability has been observed post-intervention.
DOI	10.1016/j.resplu.2025.101193
PMID	41583935