論文種別	症例報告
言語種別	英語
査読の有無	その他(不明)
表題	Surgical Treatment of Primary Localized Cutaneous Nodular Amyloidosis of the Nose: Resection and Reconstruction With a Nasolabial Flap.
掲載誌名	正式名：Cureus 略　 称：Cureus ISSNコード：21688184/21688184
掲載区分	国外
巻・号・頁	17(12),pp.e99878
著者・共著者	Daisuke Hirao, Tomoki Himejima, Michika Fukui, Masakatsu Hihara, Natsuko Kakudo
発行年月	2025/12
概要	Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare form of amyloidosis limited to the skin. A 39-year-old woman had noticed a tumor on her right nasal ala for five years. She presented it to our hospital after developing a similar lesion on her right cheek. Histopathological examination following surgical excision revealed AL amyloidosis (κ-light chain type), ruling out systemic amyloidosis and confirming the diagnosis of PLCNA. The nasal lesion was excised and reconstructed with a nasolabial flap, resulting in excellent aesthetic and functional outcomes. No recurrence has been observed during a 21-month follow-up. PLCNA in young adults is rare, and long-term follow-up is crucial due to the potential for systemic progression. This case highlights the importance of accurate diagnosis and the benefits of local flap reconstruction in cosmetically sensitive areas.
DOI	10.7759/cureus.99878
PMID	41583297