論文種別 原著(症例報告除く)
言語種別 英語
査読の有無 その他(不明)
表題 One-Year Outcome of Japanese Patients With Atrial Fibrillation: Insights From APHRS-AF Registry.
掲載誌名 正式名:Journal of arrhythmia
略  称:J Arrhythm
ISSNコード:18804276/18804276
巻・号・頁 42(1),pp.e70287
著者・共著者 Kenji Yodogawa, Yu-Ki Iwasaki, Yasuo Okumura, Koichi Nagashima, Koichi Inoue, Nobuaki Tanaka, Kengo Kusano, Koji Miyamoto, Masahiko Takagi, Kyoko Soejima, Yuichi Momose, Tomohiro Sakamoto, Hideharu Okamatsu, Toyoaki Murohara, Yasuya Inden, Keiichi Fukuda, Seiji Takatsuki, Yasuki Kihara, Yukiko Nakano, Teiichi Yamane, Michifumi Tokuda, Masayoshi Ajioka, Hiroyuki Osanai, Kazuhiro Satomi, Hiroyuki Tsutsui, Akihiko Shimizu, Satoru Sakagami, Eiichi Watanabe, Nobuhisa Hagiwara, Mitsuharu Kawamura, Naohiko Takahashi, Yoshinori Kobayashi, Hirofumi Tomita, Hiroshi Tada, Kazutaka Aonuma, Yukihiro Koretsune, Takanori Ikeda, Masahiko Goya, Wataru Shimizu
発行年月 2026/02
概要 BACKGROUND:The Asia-Pacific Heart Rhythm Society Atrial Fibrillation (APHRS-AF) Registry is a prospective study in Asian metropolitan cities, which provides important information on the baseline characteristics, therapeutic patterns, and 1-year clinical outcomes in patients with atrial fibrillation (AF). This report describes data from Japanese patients recruited in this registry.METHODS AND RESULTS:A total of 4666 patients with AF were enrolled. Of these, 794 patients were recruited from 28 large cardiovascular centers in Japan between 2015 and 2017. We analyzed 1-year follow-up outcome of these patients. Mean age at recruitment was 65.7 years and 69.0% were males. Major comorbidities were hypertension (37.5%), lipid disorder (29.0%), heart failure (15.9%), and diabetes mellitus (15.0%). Mean CHADS2 score, CHA2DS2-VASc score, and HAS-BLED score were 1.0, 2.0, and 1.1, respectively. At baseline, use of oral anticoagulants was 81%, including 7% prescribed a vitamin K antagonist (VKA) and 74% a direct oral anticoagulant (DOAC). Majority of the patients (N = 459, 57.8%) were planned to undergo catheter ablation. One-year follow-up was conducted in 743 patients. One-year all-cause mortality was 0.1% (n = 1) and the incidence of stroke/thromboembolic events was also 0.1% (n = 1). Major bleeding events were observed in 5 patients (0.7%), including 3 intracranial hemorrhages.CONCLUSION:In this 1-year analysis, a high prevalence of oral anticoagulant use was recorded. A low mortality rate and a low incidence of stroke/thromboembolic events were observed in Japanese patients of the APHRS-AF Registry.
DOI 10.1002/joa3.70287
PMID 41668691