論文種別 原著(症例報告除く)
言語種別 英語
査読の有無 その他(不明)
表題 Verification of the JRS adult pneumonia clinical practice guidelines 2024: Sensitivity and specificity of the mycoplasma pneumonia diagnostic prediction score.
掲載誌名 正式名:Respiratory investigation
略  称:Respir Investig
ISSNコード:22125353/22125345
掲載区分国外
巻・号・頁 64(3),pp.101415
著者・共著者 Naoyuki Miyashita, Makoto Ogata, Naoki Fukuda, Akihisa Yamura, Tomoki Ito
発行年月 2026/03
概要 BACKGROUND:The Japanese Respiratory Society Adult Pneumonia Clinical Practice Guidelines 2024 replaced the Atypical Pneumonia Diagnostic Prediction Score with a new diagnostic prediction score to differentiate between mycoplasmal and bacterial pneumonia. This study compared mycoplasmal and bacterial pneumonia to calculate the sensitivity and specificity of the Mycoplasma Pneumonia Diagnostic Prediction Score.METHODS:The study was conducted at five hospitals during a mycoplasmal disease outbreak and analyzed 156 cases of mycoplasmal pneumonia and 162 cases of bacterial pneumonia.RESULTS:All six items included in the diagnostic prediction score were more frequently observed in the mycoplasmal pneumonia group than in the bacterial pneumonia group. Patients in the mycoplasmal pneumonia group were significantly younger (p < 0.0001), and the prevalence of underlying diseases was significantly lower (p < 0.0001). Sputum, which was excluded from the diagnostic criteria in this study, was present in over 60% of the two groups, with no significant difference (p = 0.2957). The median white blood cell count was normal in the mycoplasmal pneumonia group and elevated in the bacterial pneumonia group (p < 0.0001). When five or more of the six diagnostic criteria were defined, the sensitivity for predicting mycoplasmal pneumonia was 71.8% and the specificity was 99.4%. Of the 44 mycoplasmal pneumonia cases that did not meet the diagnostic criteria, 38 were suspected of having mycoplasmal pneumonia based on chest computed tomography (CT) findings.CONCLUSIONS:The Mycoplasma Pneumonia Diagnostic Prediction Score was newly established as a method that emphasizes specificity, with a sensitivity of 71.8% and a specificity of 99.4%.
DOI 10.1016/j.resinv.2026.101415
PMID 41894864