| 論文種別 | 原著(症例報告除く) |
| 言語種別 | 英語 |
| 査読の有無 | その他(不明) |
| 表題 | Urinary Function After Laparoscopic Surgery in Very Low Rectal Cancer. |
| 掲載誌名 | 正式名：Diseases of the colon and rectum 略 称：Dis Colon Rectum ISSNコード：15300358/00123706 |
| 掲載区分 | 国外 |
| 著者・共著者 | Yosuke Fukunaga, Yuichiro Tsukada, Takashi Akiyoshi, Tomohiro Yamaguchi, Jun Watanabe, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Masanori Yoshimitsu, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Takeshi Naitoh, Masahiko Watanabe, Motoko Suzuki, Toshihiro Misumi, Masaaki Ito, |
| 発行年月 | 2026/03 |
| 概要 | BACKGROUND:Only few reports have exclusively assessed urinary function after laparoscopic rectal surgery, despite long-term investigations.OBJECTIVE:To investigate urinary function after laparoscopic low rectal cancer surgery using three types of questionnaires collected during a prospective clinical phase II trial (ULTIMATE trial) involving 47 Japanese hospitals.DESIGN:Prospective.SETTING:Japanese tertiary hospitals.PATIENTS:A total of 300 patients undergoing laparoscopic low rectal cancer surgery.MAIN OUTCOME MEASURES:Residual urine was measured twice daily on postoperative days 5-7. The International Prostate System Score, Overactive Bladder Symptom Score, and International Consultation on Incontinence Questionnaire-Short Form scoring were used to evaluate urinary disorders.RESULTS:Short-term voiding dysfunction was diagnosed in 78 patients and was associated with surgery duration, which was the only factor affecting voiding function in multivariate analysis. The differences in International Prostate System Score before and after surgery were significantly larger in patients who underwent abdominoperineal resection; in these patients, the urinary function did not recover over time. The mean International Prostate System Score of patients aged >75 years was significantly worse postoperatively than before surgery, and the differences were significantly larger in the older group than those in the younger group. In the multivariate analysis, the type of surgery, abdominoperineal resection, and age >75 years were significant factors affecting the International Prostate System Score after surgery. There were no significant differences in the Overactive Bladder Symptom Score or International Consultation on Incontinence Questionnaire-Short Form score after surgery, even with respect to the clinical and operative variables.LIMITATIONS:The trial was limited only to early stage rectal cancer and recruited patients from 47 hospitals with a range of surgical techniques.CONCLUSIONS:Our finding indicated urinary function deterioration in those who underwent abdominoperineal resection and those with advanced age after laparoscopic surgery for early low rectal cancer. See Video Abstract.Clinical trial registration: UMIN000011750. |
| DOI | 10.1097/DCR.0000000000004221 |
| PMID | 41870086 |