| 論文種別 | 原著(症例報告除く) |
| 言語種別 | 英語 |
| 査読の有無 | その他(不明) |
| 表題 | The Perfusion Index May be an Accurate Tool for Predicting the Progression of Ischemia in Patients with Peripheral Arterial Disease. |
| 掲載誌名 | 正式名：Angiology 略 称：Angiology ISSNコード：19401574/00033197 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.Online ahead of print |
| 著者・共著者 | Hiroyoshi Komai, Yuka Kitaoka, Nobuko Yamamoto, Islam Atta, Masato Ohno, Noriyuki Miyama, Noriyasu Morikage, Tadaaki Koyama |
| 発行年月 | 2026/05 |
| 概要 | To test the reliability of the perfusion index (PI), a new index of blood flow in the lower extremities, we studied 246 patients (368 legs) with ischemic foot symptoms between January 2020 and November 2024. The average PI (PIave) was measured with a saturation monitor probe applied to all toes. The PIave value was obtained within 5 minutes for each foot and decreased as the ischemia severity increased. Skin perfusion pressure was significantly positively correlated with PIave (r = .215; P < .001). Of the 201 limbs of conservatively treated patients, 12 of 74 limbs with a PIave < .27 progressed to chronic limb-threatening ischemia (CLTI), while only 2 of 127 limbs with a PIave ≥ .27 progressed (χ2 test; P < .001; negative predictive value: 98%). Logistic regression analysis revealed that PIave < .27 was significantly associated with disease progression. In conclusion, the PI is a simple and useful marker for accurately indicating the degree of ischemia in the toes. The PI can predict that a patient will not progress to CLTI in the next 3 months with conservative treatment and may contribute to safe follow-up. |
| DOI | 10.1177/00033197261447018 |
| PMID | 42093653 |