論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	その他(不明)
表題	Postoperative Abscesses in the Liver Resection Plane in Patients with a History of Biliary Tract Treatments: A Multicenter Cohort Study.
掲載誌名	正式名：Asian Pacific journal of cancer prevention : APJCP 略　 称：Asian Pac J Cancer Prev ISSNコード：2476762X/15137368
掲載区分	国外
巻・号・頁	27(6),pp.2043-2052
著者・共著者	Hiroya Iida, Hiroji Shinkawa, Hisashi Kosaka, Masaki Ueno, Haruki Mori, Koji Komeda, Satoshi Yasuda, Masahiko Kinoshita, Shinya Hayami, Masaji Tani, Masaki Kaibori, Shoji Kubo
発行年月	2026/06
概要	OBJECTIVE:The effect of previous biliary reconstruction (BR) or endoscopic sphincterotomy (EST) on post-hepatectomy bile leakage and abscess formation remains controversial. This study aimed to investigate the incidence, clinical findings, and risk factors of postoperative abscesses in the liver resection plane in patients with such histories.METHODS:This multicenter retrospective study included 5,742 patients who underwent liver resection between 2011 and 2020 (38 with a history of BR, 44 with EST, and 5,660 with no history of biliary treatment). The incidence, clinical characteristics, and risk factors for abscess formation, as well as factors associated with prolonged healing duration (≥45 days), were analyzed.RESULTS:Abscess formation was significantly more frequent in the BR (47.4%) and EST (25.0%) groups than in the non-BR/non-EST group (3.5%). Bile leakage was identified as an independent risk factor for abscess formation. Bile leakage and mixed infection both significantly more frequent in the BR group than in the non-BR/non-EST group were independent risk factors for prolonged healing duration.CONCLUSION:Patients with a history of BR or EST are at a higher risk of postoperative abscess formation in the liver resection plane. Bile leakage plays a critical role in both abscess development and prolonged healing.
DOI	10.31557/APJCP.2026.27.6.2043
PMID	42345150