論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	その他(不明)
表題	Palliative Care Team Involvement Is Associated with Changes in Nutrition Impact Symptoms and Eating-Related Distress in Patients with Advanced Cancer: A Multicenter Prospective Observational Study.
掲載誌名	正式名：Nutrients 略　 称：Nutrients ISSNコード：20726643/20726643
掲載区分	国外
巻・号・頁	18(13),pp.2174
著者・共著者	Koji Amano, Saori Koshimoto, Tatsuma Sakaguchi, Akihiro Tokoro, Sayaka Arakawa, Takashi Takeuchi, Naoharu Mori, Yoshinobu Matsuda, Eriko Satomi, Haruka Harano, Mitsunori Miyashita
発行年月	2026/07
概要	OBJECTIVES:Evidence on the effects of palliative care team interventions on cachexia remains limited. We examined the effects on nutrition impact symptoms (NISs), dietary intake, and eating-related distress (ERD) among advanced cancer patients.METHODS:This was a multicenter prospective observational study. Participants completed the baseline survey and the follow-up survey one week later. They evaluated NISs, dietary intake, and ERD. We compared the patient-reported outcomes between the two surveys. We categorized the participants having four or more NISs with a score ≥ 4 into the High-NIS group (otherwise, the Low-NIS group) using their baseline scores. Changes in the number of symptoms with a score ≥ 4, the dietary intake, and the ERD scores were calculated. Multiple regression analyses were performed to identify the factors influencing the improvements in dietary intake and ERD.RESULTS:A total of 123 patients were included. In all patients, pain, fatigue, lack of appetite, sadness, and ERD significantly improved (p = 0.001, 0.023, 0.043, 0.037, <0.001). In the High-NIS group, the number of symptoms with a score ≥ 4 significantly decreased (p = 0.009), dietary intake scores significantly increased (p = 0.037), and ERD scores significantly decreased (p = 0.001). The number of symptoms with a score ≥ 4 at baseline (B = 1.08, p = 0.044, 95% confidence interval 0.03 to 2.14) was the only independent factor influencing the improvements in dietary intake.CONCLUSIONS:NISs and ERD improvements were associated with the interventions. Dietary intake improvement was associated with a high baseline symptom burden.
DOI	10.3390/nu18132174
PMID	42451174