教員別検索 - 木梨　達雄

1.	原著(症例報告除く)	ARAP1 fine-tunes F-actin polymerization level in lymphocytes through RhoA inhibition. 2025/12
2.	原著(症例報告除く)	The non-conserved integrin cytoplasmic region determines integrin subtype-specific characteristics by modulating talin1 binding kinetics. 2025/11
3.	原著(症例報告除く)	Weak and Tunable Adhesion-Clutch Drives Rapid Cell Migration and Glioblastoma Invasion. 2025/10
4.	原著(症例報告除く)	The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling 2025/02
5.	原著(症例報告除く)	Low-affinity LFA1-dependent outside-in signaling mediates avidity modulation via the Rabin8-Rab8 axis 2024/08
6.	その他	Rap1活性化調節によるリンパ球の移動制御 2024/06
7.	原著(症例報告除く)	Rhodium-catalyzed homo-coupling reaction of aryl Grignard reagents and its application for the synthesis of an integrin inhibitor 2024/06
8.	原著(症例報告除く)	Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1 2023/07
9.	原著(症例報告除く)	The critical role of Rap1-GAPs Rasa3 and Sipa1 in T cells for pulmonary transit and egress from the lymph nodes 2023/07
10.	原著(症例報告除く)	Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization 2023/07
11.	原著(症例報告除く)	Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow 2023/06
12.	総説	LFA1 Activation: Insights from a Single-Molecule Approach 2022/05
13.	総説	Kindlin-3はインテグリンLFA-1のサブユニット間の会合を阻害してRap1およびtalin1による正のフィードバックを活性化させる 2022/03
14.	原著(症例報告除く)	Kindlin-3 disrupts an intersubunit association in the integrin LFA1 to trigger positive feedback activation by Rap1 and talin1 2021/06
15.	原著(症例報告除く)	Effect of Learning Dataset for Identification of Active Molecules: A Case Study of Integrin αIIbβ3 Inhibitors 2021/03
16.	総説	インテグリン創薬から考える一回膜貫通型タンパク質における創薬ストラテジー 2020/10
17.	総説	MST1/2 Balance Immune Activation and Tolerance by Orchestrating Adhesion, Transcription, and Organelle Dynamics in Lymphocytes 2020/05
18.	総説	【ジーンハンティングによる炎症・免疫研究の発展】IL-4およびIL-5の遺伝子クローニング 2020/04
19.	総説	白血球インテグリンによる接着の制御機構 2019/08
20.	原著(症例報告除く)	Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs. 2018/12
21.	原著(症例報告除く)	Live-Cell FRET Imaging Reveals a Role of Extracellular Signal-Regulated Kinase Activity Dynamics in Thymocyte Motility. 2018/11
22.	原著(症例報告除く)	Visualizing the Rapid and Dynamic Elimination of Allogeneic T Cells in Secondary Lymphoid Organs. 2018/08
23.	総説	自己免疫疾患のイメージング：自己寛容の成立と維持における細胞間相互作用の可視化 2018/04
24.	原著(症例報告除く)	Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen 2017/12
25.	原著(症例報告除く)	Mst1欠損による増強された細胞障害性T細胞の機能と腫瘍発達の抑制 2017/12
26.	原著(症例報告除く)	NDR1-Dependent Regulation of Kindlin-3 Controls High-Affinity LFA-1 Binding and Immune Synapse Organization 2017/03
27.	原著(症例報告除く)	Microenvironmental Control of High-Speed Interstitial T Cell Migration in the Lymph Node 2016/05
28.	原著(症例報告除く)	The RacGAP protein FilGAP is a negative regulator of chemokine-promoted lymphocyte migration 2016/05
29.	原著(症例報告除く)	Sema3e/Plexin D1 Modulates Immunological Synapse and Migration of Thymocytes by Rap1 Inhibition 2016/04
30.	原著(症例報告除く)	Enhanced cytotoxic T-cell function and inhibition of tumor progression by Mst1 deficiency 2016/01
31.	原著(症例報告除く)	Hypermethylation of MST1 in IgG4-related autoimmune pancreatitis and rheumatoid arthritis 2015/08
32.	原著(症例報告除く)	Integrin LFA-1 regulates cell adhesion via transient clutch formation 2015/08
33.	総説	免疫細胞のHippo Pathway 2014/11
34.	原著(症例報告除く)	Autotaxin produced by stromal cells promotes LFA-1-independent and Rho-dependent interstitial T cell motility in the lymph node paracortex 2014/07
35.	原著(症例報告除く)	Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking. 2014/07
36.	総説	リンパ球の高速移動を制御するリンパ節組織支持細胞ネットワーク 2014/05
37.	総説	免疫細胞の動態制御とストローマ細胞リンパ節における高速T細胞遊走と組織環境 2013/12
38.	原著(症例報告除く)	Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase. 2013/11
39.	原著(症例報告除く)	Antigen-specific suppression and immunological synapse formation by regulatory T cells require the mst1 kinase. 2013/09
40.	原著(症例報告除く)	HTLV-1 bZIP Factor Induces Inflammation through Labile Foxp3 Expression. 2013/09
41.	原著(症例報告除く)	Dendritic Cells Regulate High-Speed Interstitial T Cell Migration in the Lymph Node via LFA-1/ICAM-1. 2013/08
42.	原著(症例報告除く)	Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis. 2013/05
43.	総説	Mst1による胸腺細胞のインテグリン接着制御と選択機構 2013
44.	原著(症例報告除く)	Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus. 2012/10
45.	原著(症例報告除く)	Reelin Controls Neuronal Positioning by Promoting Cell-Matrix Adhesion via Inside-Out Activation of Integrin α5β1. 2012/10
46.	原著(症例報告除く)	Surf4 modulates STIM1-dependent calcium entry. 2012/06
47.	原著(症例報告除く)	DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses. 2012/05
48.	総説	インテグリン制御によるリンパ球動態 2012/04
49.	原著(症例報告除く)	Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. 2012/02
50.	原著(症例報告除く)	Overview of integrin signaling in the immune system. 2011/07
51.	原著(症例報告除く)	Rap1 and integrin inside-out signaling. 2011/07
52.	原著(症例報告除く)	Deficiency of Rap1-Binding Protein RAPL Causes Lymphoproliferative Disorders through Mislocalization of p27kip1. 2011/01
53.	総説	免疫in vivoイメージング-免疫疾患のダイナミクス研究へリンパ節へのリンパ球のエントリーとmigrationのイメージング-リンパ球動態制御分子の機能解析 2010/03
54.	原著(症例報告除く)	Rap1 controls lymphocyte adhesion cascades and interstitial migration within lymph nodes in RAPL-dependent and -independent manners. 2010/01
55.	原著(症例報告除く)	Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes. 2009/05
56.	原著(症例報告除く)	CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways 2009/04
57.	原著(症例報告除く)	Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs. 2008/11
58.	総説	リンパ組織の構造と免疫細胞の動態制御 03 二次リンパ器官におけるストローマ細胞ネットワークとリンパ球の動態制御 2008/09
59.	総説	接着分子による免疫細胞動態調節と免疫応答 2008/06
60.	総説	低分子量G蛋白質Rap1によるインテグリンの制御 2007/10
61.	原著(症例報告除く)	The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytes. 2007/08
62.	総説	免疫学　接着分子による免疫細胞動態調節(Rap1-RAPLとSTK4/Mst1) 2007/02
63.	総説	Integrin regulation of lymphocyte trafficking: lessons from structural and signaling studies. 2007
64.	原著(症例報告除く)	Adhere Upright: A Switchblade-like Extension of β2 Integrins. 2006
65.	原著(症例報告除く)	Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion. 2006
66.	総説	2章抗原認識,co-receptor Rap1/RAPL相互作用による血液系細胞の生体内動態制御 2005/12
67.	総説	免疫学　インテグリン接着制御分子RAPLによる免疫細胞動態制御 2005/02
68.	原著(症例報告除く)	CXCL13 is an arrest chemokine for B cells in high endothelial venules. 2005
69.	総説	Intracellular signalling controlling integrin activation in lymphocytes. 2005
70.	原著(症例報告除く)	Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues. 2005
71.	総説	【リンパ球ホ-ミングの分子機構最近の展開】免疫細胞の動態制御因子Rap1/RAPL 2005
72.	総説	Rap1エフェクター分子RAPLによる免疫細胞の動態制御 2004/12
73.	原著(症例報告除く)	Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking. 2004/10
74.	総説	Rap1エフェクター分子RAPLによる免疫細胞動態調節 2004/10
75.	原著(症例報告除く)	LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds. 2004/02
76.	原著(症例報告除く)	RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1. 2003/08
77.	原著(症例報告除く)	Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity. 2003/07
78.	原著(症例報告除く)	The critical cytoplasmic regions of the αL/β2 integrin in Rap1-induced adhesion and migration. 2003/06
79.	原著(症例報告除く)	Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. 2003/04
80.	原著(症例報告除く)	Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses. 2002/02
81.	原著(症例報告除く)	Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase. 2000/03
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